Search results for "Laryngeal oedema"

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Treatment of skin swellings with C1-inhibitor concentrate in patients with hereditary angio-oedema.

2008

Background:  Skin swellings are the most frequent symptoms in hereditary angio-oedema (HAE) arising out of C1-inhibitor (C1-INH) deficiency. They may be painful and impact daily activities of patients. Detailed clinical data concerning the treatment of skin swellings by C1-INH concentrate have not been reported yet. Methods:  From 1976 through 2007, a total of 2104 skin-swelling attacks in 47 patients with HAE were treated with the C1-INH concentrate. Time to relief and duration of the swellings were documented during personal interviews using standardized questionnaires. The results were compared with 9046 untreated skin swellings in the same patients. Results:  The first clinical sign of …

AdultMaleAllergymedicine.medical_specialtyHereditary angio-oedemaAdolescentImmunologyC1-inhibitorImmunopathologyImmunology and AllergyMedicineHumansIn patientProspective StudiesChildAgedRetrospective StudiesSkinbiologybusiness.industryAngioedemas HereditaryDrug administrationMiddle Agedmedicine.diseaseTrunkSurgerybiology.proteinFemaleLaryngeal oedemabusinessComplement C1 Inhibitor ProteinAllergy
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